. It discusses representative drugs by example to explore the range of biochemical targets and mechanisms. Subscribers may reproduce tables of contents or prepare lists of articles including abstracts for internal circulation within their institutions. Pick the true statement: a Amox- Clavulanic, Clavulanic increases amox activity b Sublactum is used in treatment of Leprosy c Aztreonam is a metabolite of clarithromycin d Cilastatin imipenam- cilastatin prevents hydrolysis of imipenam Ans:b 53. The chemical structure of all novel compounds tested must be included in the submitted manuscript or be readily accessible in the published literature. Respiratory difficulties are often complicated by lung infections. Biochemical Pharmacology can also serve as an introduction for professionals in biosciences, as well as in pharmaceutical and health sciences.
For each drug discussed, the authors provide the biochemical concepts needed to understand its function. Are the sources of all materials clearly indicated? Is a conflict of interest statement included in the manuscript? The elimination of following drugs is dose dependant except a Phenytoin b Salicylate c Theophylline d Chlorpromazine Ans:d 47. The embargo period for this journal can be found below. Which of the following drugs is associated with the reaction of Stevens-Johnson syndrome? Preface Acknowledgments 1 Introduction 1. While medicinal chemistry is a topic of complimentary interest, manuscripts in this area must contain sufficient biological data to characterize pharmacologically the compounds reported. For gold open access articles: Upon acceptance of an article, authors will be asked to complete an 'Exclusive License Agreement'.
The following drug is not secreted in bile a Penicillin b Phenolphthalein c Novobiocin d Erythromycin Ans:a 21. Drug classes covered include anti-infectives, anti-inflammatory agents, chemotherapeutics, cardiovascular, endocrinological, immunological, metabolic, neurological and psychiatric drugs, as well as research on drug metabolism and kinetics. Has the species, strain, sex, weight and source of the animals been provided? Offprints The corresponding author will, at no cost, receive a customized providing 50 days free access to the final published version of the article on. John Honek, PhD, is Professor in the Department of Chemistry at the University of Waterloo, associate editor for Future Medicinal Chemistry and Biochemistry and Cell Biology, and serves on the editorial boards of BioMed Central Biochemistry, Current Medicinal Chemistry, and Letters in Drug Design and Discovery. Types of papers 1 Full-length Research Papers.
Tables should appear individually on separate pages in the submitted version of the work, together with a legend that includes sufficient information about the experimental protocol and results so the reader does not have to refer back to the text to understand the experimental protocol and findings. Which phenothiazine has the least extra pyramidal effect a Thioridazine b Chlorpromazine c Triflupromazine d Fluphenazine Ans:a 81. Green open access Authors can share their research in a variety of different ways and Elsevier has a number of green open access options available. Drug levels should be monitored in the treatment of a Diabetes b Epilepsy c Status Asthmatics d Hypertension Ans:b 8. Proofreading is solely your responsibility. Articles should make no assumptions about the beliefs or commitments of any reader, should contain nothing which might imply that one individual is superior to another on the grounds of race, sex, culture or any other characteristic, and should use inclusive language throughout.
Authors can have their manuscript language-edited. The book explains some of the experiments that tell us how drugs work, and it outlines the physiological and pathological context that make those action mechanisms therapeutically useful. No physical dependence is seen in: a Dextropropoxyphene b Fortwin c Fluoxetine d Alprax Ans:c 66. Using a more chemistry- and mechanism-oriented approach than standard pharmacology books, Introduction to Biochemical Pharmacology is a one-stop reference that focuses on how a drug interacts with a target receptor or enzyme at the molecular level. Nicotinic receptors are seen in a Skeletal muscle b Visceral smooth muscle c Cardiac muscle d Salivary glands Ans:a 97. It is written in a conversational, vivid style that readily encourages students to explore this important area of medical science.
Xenobiotics is characterized by chemicals, such as drugs, that are inherently foreign to a living organism. Idiosyncrasy is: a A genetically determined abnormal reaction to drugs b A characteristic toxic effect at therapeutic doses c An altered physiological state produced by repeated drug use d An immunologically mediated reaction Ans:a 19. For classroom use, the illustrations from the book are separately available as PowerPoint slides. If used, is the method of anesthesia described? Are the limitations of the current study or alternative interpretations of the findings clearly stated? Are the primary endpoints clearly stated? Least half life is for which hormone a Nor adrenaline b Renin c Aldosterone d Thyroxine Ans:a 64. It discusses representative drugs by example to explore the range of biochemical targets and mechanisms. They are found mainly in the extracellular matrix.
Which of the following is not a dose related reaction: a Myocardial Irritation of Quinidine b Hypoglycemia of tolbutamide c Digitalis induced arrythmia d Drug fever of sulpha Ans:d 56. Which statement is false of Domperidone a Chemically related to haloperidol b Pharmacologically related to metoclopramide c Extra pyramidal symptoms are common d It counteracts the emetic action but not the therapeutic effect in parkinsonism Ans:c 75. Reference formatting There are no strict requirements on reference formatting for the initial submission. Complete with numerous figures throughout the text, which are also available separately as PowerPoint slides, Biochemical Pharmacology : Explains the role of pharmacodynamics, pharmacokinetics, and drug metabolism in drug action Provides representative examples from the pharmacology of cell excitation, hormones, nitric oxide, chemotherapy, and others Examines emerging applications of ribonucleic acids as drugs and drug targets Discusses what researchers need to know about the problems of drug distribution, elimination, and toxicity Biochemical Pharmacology is an important resource for anyone wishing to gain an in-depth understanding of drug action mechanisms and extremely useful for researchers wishing to explore some of the unanswered questions. Some Of course, there are many different apple pies, and many different serving portions too!!! They explain some of the experimental methods used to characterize drugs and their receptors, together with examples of the evidence that these methods provide. It is written in a conversational, vivid style that readily encourages students to explore this important area of medical science. An e-mail will be sent to the corresponding author confirming receipt of the manuscript together with a 'Journal Publishing Agreement' form or a link to the online version of this agreement.
Zero order kinetics is seen with a Phenytoin b Phenobarbital c Erythromycin d Digoxin Ans:a 40. Is the rationale for the selection of concentrations, doses, route and frequency of compound administration provided? Which of the following shows high first pass metabolism: a Propranolol b Phenobarbitone c Phenylbutazone d Phenytoin e Reflex esophagitis Ans:a 62. Complete with numerous figures throughout the text, which are also available separately as PowerPoint slides, Biochemical Pharmacology: Explains the role of pharmacodynamics, pharmacokinetics, and drug metabolism in drug action Provides representative examples from the pharmacology of cell excitation, hormones, nitric oxide, chemotherapy, and others Examines emerging applications of ribonucleic acids as drugs and drug targets Discusses what researchers need to know about the problems of drug distribution, elimination, and toxicity Biochemical Pharmacology is an important resource for anyone wishing to gain an in-depth understanding of drug action mechanisms and extremely useful for researchers wishing to explore some of the unanswered questions. This summary statement will be ultimately published if the article is accepted. Authors must supply the graphic separately as an electronic file. Drugs mostly cross biological membranes by a Passive diffusion b Active diffusion c Active transport d Carrier mediated transport e All of the above Ans:a 31.
Authors can quickly and easily transfer their research from a Partner Journal to Heliyon without the need to edit, reformat or resubmit. The Acknowledgments should include the names of individuals, organizations and funding agencies that provided assistance in underwriting and reporting the work. Pompe disease is a rare estimated at 1 in every 40,000 births , inherited and often fatal disorder that disables the heart and muscles. As a result, an enzyme replacement therapy has been developed that has shown, in clinical trials with infantile-onset patients, to decrease heart size, maintain normal heart function, improve muscle function, tone, and strength, and reduce glycogen accumulation. Finally, the authors point out some of the questions that remain to be solved by future researchers. Stonehill : -These guys make me feel old. Cite underlying or relevant datasets in your text and include a data reference in your Reference List.
Enterohepatic circulation is seen in a Ampicillin b Benzylpenicillin c Norfloxacin d Streptomycin Ans:d 63. Data references should include the following elements: author name s , dataset title, data repository, version where available , year, and global persistent identifier. Graphical Abstract Authors asked to submit a revised version of the work for consideration must also supply a graphical abstract at that time. Kids with names, dreams, families that love them. He has written over forty articles, papers, abstracts, and presentations. Are the primary conclusions and any secondary endpoints and their implications clearly stated? Formatting — Only video or audio files may be uploaded as supplementary data.